CAP Member Adam Cloe, MD, FCAP, explains the silent inactivation of E. coli asparaginase. “In silent inactivation, the anti-asparaginase antibodies don't cause an allergic reaction but do neutralize the asparaginase, so it no longer works,” said Dr. Cloe.
For the full article click here: The silent inactivation phenomenon in E. coli asparaginase therapy